Ameliorative Effect of Silymarin on Scopolamine-induced Dementia in Rats
نویسندگان
چکیده
منابع مشابه
the effect of aqueous extract of garlic on formalin-induced pain in male rats
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15 صفحه اولAmeliorative Effect of Silymarin Against Radiation- Induced Oxidative Stress in the Liver of Male Rats
Administration of dietary antioxidants has been suggested to protect against liver tissue damage induced by radiation exposure. Silymarin is a polyphenolic plant flavonoid derived from Silymarin marianum that has hepatoprotective and anticarcinogenic effects. Therefore, the present study was carried out to investigate the radioprotective activity of Silymarin against radiation-induced liver dam...
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Numerous studies conducted in laboratory animals and humans indicate that angiotensin converting enzyme inhibitors reinforce memory and learning. In this paper we study the effect of injection of enalapril into the cerebral ventricles on spatial memory of white mice in the double- y maze, following the induction of an Alzheimer- like amnestic model with scopolamine. To estimate the duration o...
متن کاملAmeliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway
Objective(s): Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and antioxidant effects; however its role in aspiration induced ALI has not b...
متن کاملThe effect of intracerebroventricular administration of insulin on memory impairment-induced by scopolamine in male rats
Introduction: Cholinergic neuronal deficiency is one of the main causes of Alzheimer's pathology, which leads to learning and memory impairment. Scopolamine is a muscarinic cholinergic antagonist commonly used to induce Alzheimer's disease (AD). Insulin also regulates learning and memory function. Thus, the aim of this study was to determine the effect of central administration of insulin on pa...
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2018
ISSN: 1857-9655
DOI: 10.3889/oamjms.2018.257